DocumentCode :
1669452
Title :
Dispersion of repolarisation and the T wave: a computer model
Author :
Bernardo, D. Di ; Murray, A.
Author_Institution :
Regional Med. Phys. Dept., Freeman Hosp., Newcastle upon Tyne, UK
fYear :
1999
fDate :
6/21/1905 12:00:00 AM
Firstpage :
65
Lastpage :
68
Abstract :
A simple mathematical model of repolarisation of the left ventricle is presented. The T wave on the surface electrocardiogram is simulated. The model is applied to the study of increased dispersion of repolarisation that has been shown to be a substrate for fatal arrhythmias. Results from the model show that symmetrical and tall pathological T waves are a product of increased dispersion of repolarisation in the left ventricle. The end of the simulated T waves is the same in all 12 leads, suggesting that QT dispersion (defined as the differences of QT intervals in the 12 standard leads) is not a good measure of dispersion of repolarisation. The symmetry ratio, (SR), which measures the symmetry of the T wave, is shown to be a good candidate. The model predicts a value of SR close to 1.5 for small values of dispersion. This result is in agreement with the mean value of the symmetry ratio in normal subjects as reported in literature. For increasing values of dispersion, SR from. The model decreases towards value close to 1, demonstrating the source of the more symmetrical T waves in these patients
Keywords :
digital simulation; electrocardiography; medical diagnostic computing; physiological models; ECG; QT dispersion; cardiac electrophysiology; computer model; fatal arrhythmias substrate; left ventricle; more symmetrical T waves; repolarisation dispersion; symmetry ratio; tall pathological T waves; Conductivity; Dispersion; Ellipsoids; Equations; Extracellular; Heart rate interval; Myocardium; Physics; Strontium; Torso;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computers in Cardiology, 1999
Conference_Location :
Hannover
ISSN :
0276-6547
Print_ISBN :
0-7803-5614-4
Type :
conf
DOI :
10.1109/CIC.1999.825907
Filename :
825907
Link To Document :
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