Title :
A Non-EST-Based Method for Alternative 5´/3´ Splice Sites Prediction in the Mouse Genome
Author :
Yang, Wuritu ; Li, Qian-zhong
Author_Institution :
Dept. of Phys., Inner Mongolia Univ., Hohhot
Abstract :
The identification of alternative splice site in the mouse genome is an important part of the recent alternative splicing event prediction work. In this paper, a non-EST-based predicting method is proposed for alternative 5´/3´ splice sites identification. Only based on local sequence features, more than 72% of alternative splice sites and constitutive splice sites can be correctly classified in the mouse genome.
Keywords :
genetics; medical computing; molecular biophysics; pattern classification; proteins; support vector machines; alternative 5´/3´ splice site prediction; local sequence features; mouse genome classification; nonexpressed sequence tag-based method; protein product; support vector machine; Bioinformatics; Diversity reception; Genomics; Humans; Mice; Proteins; Splicing; Support vector machine classification; Support vector machines; Testing;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.804
