Title :
Computational models of cardiovascular function for analysis of post-flight orthostatic intolerance
Author :
Heldt, T. ; Shim, Eb ; Kamm, RD ; Mark, RG
Author_Institution :
MIT, Cambridge, MA, USA
fDate :
6/21/1905 12:00:00 AM
Abstract :
The work presented in this paper is part of an ongoing effort to use mathematical models to investigate the effects of microgravity on the cardiovascular system. In particular a thirteen compartment lumped parameter representation of the cardiovascular system is used to simulate some of the current hypotheses concerning the mechanism of post-flight orthostatic intolerance. Simulations are compared to astronaut stand test data pre- and post-flight in an effort to quantitatively evaluate alternative hypotheses
Keywords :
aerospace biophysics; biocontrol; cardiovascular system; haemodynamics; medical computing; physiological models; astronaut stand test data; cardiovascular function; computational models; mathematical models; microgravity effects; post-flight orthostatic intolerance; pre-flight; thirteen compartment lumped parameter representation; Blood flow; Blood pressure; Cardiology; Cardiovascular system; Computational modeling; Heart rate; Hemodynamics; Mathematical model; Pressure control; Stress;
Conference_Titel :
Computers in Cardiology, 1999
Conference_Location :
Hannover
Print_ISBN :
0-7803-5614-4
DOI :
10.1109/CIC.1999.825944
