Application of the dual sequence method to estimate the baroreflex sensitivity in patients with dilated cardiomyopathy

Author

Voss, A. ; Baier, V. ; Malberg, H. ; Wessel, N. ; Hasart, A. ; Reinsperger, F. ; Schirdewan, A. ; Osterziel, KJ

Author_Institution

Univ. of App. Scis., Jena, Germany

fYear

1999

fDate

6/21/1905 12:00:00 AM

Firstpage

221

Lastpage

224

Abstract

This study aims to estimate the spontaneous baroreflex sensitivity (BRS) with two different methods in patients with dilated cardiomyopathy (DCM). The new Dual Sequence Method (DSM) contains the analysis of spontaneous fluctuations of systolic blood pressure (SEP) and the corresponding beat-to-beat intervals (BBI) of heart rate (HR). Bradycardic as well as tachycardic fluctuations were considered for synchronized and a three beats shifted BBI-sequence. Whereas the established Z-coefficient method investigates the statistical dependence between SEP and HR values. The BRS and the number of fluctuations with a slope >5 msec/mmHg calculated by the DSM are significant lower (p<0.05) in DCM patients than in controls. Thus, the DSM leads in contrast to the Z-coefficient method to an improved precision in characterizing DCM patients

Keywords

blood pressure measurement; cardiology; diseases; electrocardiography; muscle; ECG; Z-coefficient method; baroreflex sensitivity estimation; beat-to-beat intervals; bradycardic fluctuations; dilated cardiomyopathy patients; dual sequence method; heart rate; spontaneous fluctuations analysis; statistical dependence; systolic blood pressure; tachycardic fluctuations; Baroreflex; Biomedical monitoring; Blood pressure; Cardiac disease; Cardiology; Drugs; Electrocardiography; Fluctuations; Heart rate; Time measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 1999

Conference_Location

Hannover

ISSN

0276-6547

Print_ISBN

0-7803-5614-4

Type

conf

DOI

10.1109/CIC.1999.825946

Filename

825946