Spectral coherence of ventricular fibrillation under conditions of coronary perfusion, dilatation and drug administration

Author

Guerrero, J. ; Chorro, Fj ; Rosado, A. ; Magdalena, R. ; Soria, E. ; Bataller, M. ; Lopez-Merino, V. ; Espi, J.

Author_Institution

Dpto. Inf. y Electron., Valencia Univ., Spain

fYear

1999

fDate

6/21/1905 12:00:00 AM

Firstpage

339

Lastpage

342

Abstract

In this paper, modifications of spectral coherence for ventricular fibrillation (VF) in the isolated rabbit heart are investigated under coronary perfusion, ventricular dilatation, and the administration of antiarrhythmic drugs (verapamil). Obtained results for the mean magnitude-squared coherence function (MMSC) show that: (i) it decreases during dilatation, and increases in post-dilatation; (ii) the verapamil increases MMSC, but partially counteracts the increment induced by post-dilatation

Keywords

electrocardiography; medical signal processing; spectral analysis; antiarrhythmic drugs; coronary perfusion; cross-spectrum; drug administration; isolated rabbit heart; mean magnitude-squared coherence function; post-dilatation; spectral coherence; ventricular dilatation; ventricular fibrillation; verapamil administration; Cardiology; Drugs; Electrodes; Electronics packaging; Electrophysiology; Fibrillation; Heart; Hospitals; Rabbits; Signal processing;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 1999

Conference_Location

Hannover

ISSN

0276-6547

Print_ISBN

0-7803-5614-4

Type

conf

DOI

10.1109/CIC.1999.825976

Filename

825976