Title :
Localization and Atlas-Based Segmentation of the Heart from Cardiac MR Images: Validation with a Large Clinical Trial
Author :
Lin, Xiang ; Young, Alistair ; Cowan, Brett
Author_Institution :
Auckland Bioeng. Inst., Univ. of Auckland, Auckland
Abstract :
This paper presents an automatic method to find and segment the boarders of the left and right ventricles (LV and RV) from the middle short axis (SA) slice of a functional cardiac MRI study. The segmentation is implemented using a new atlas-based registration framework which is able to integrate boundary, intensity and anatomical information. The method is shown to be accurate, robust and reliable in a clinical trial of 330 patients with a range of cardiac and vascular disease. The method failed in only two cases, and showed high agreement with expert observers in the remaining 328.
Keywords :
biomagnetism; biomedical MRI; cardiovascular system; diseases; image segmentation; atlas-based segmentation; cardiac disease; functional cardiac MR images; heart; left ventricle; middle short axis slice; right ventricle; vascular disease; Blood; Clinical trials; Heart; Image segmentation; Interpolation; Labeling; Magnetic resonance imaging; Muscles; Myocardium; Robustness;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.912