• DocumentCode
    1673228
  • Title

    Spectrally multiplexed photothermal OCT and novel detection methods

  • Author

    Kim, Sanghoon ; Rinehart, Matthew T. ; Zhu, Yizheng ; Wax, Adam

  • Author_Institution
    Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA
  • fYear
    2012
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We demonstrate simultaneous detection of two nanoparticle species using phase-sensitive optical coherence tomography with photothermal excitation at two wavelengths matched to the distinct absorption peaks of the nanoparticles. To minimize bulk heating of the sample, a novel single-pulse excitation scheme is proposed and its sensitivity is characterized.
  • Keywords
    biomedical optical imaging; biothermics; gold; heating; nanomedicine; nanoparticles; optical tomography; photothermal effects; silver; Ag; Au; gold nanoparticles; heating; novel detection method; novel single-pulse excitation scheme; phase-sensitive optical coherence tomography; photothermal excitation; silver nanoparticles; spectrally multiplexed photothermal OCT; Gold; Heating; Nanoparticles; Optical imaging; Optical sensors; Phase measurement; Signal to noise ratio;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2012 Conference on
  • Conference_Location
    San Jose, CA
  • Print_ISBN
    978-1-4673-1839-6
  • Type

    conf

  • Filename
    6326401