Title :
Hybridization of ODNs with core-shell structure of Fe3O4 nanoparticles and CSALG composite structure
Author :
Chang, Ho ; Lin, LinWei
Author_Institution :
Dept. of Mech. Eng., Nat. Taipei Univ. of Technol., Taipei, Taiwan
Abstract :
This study attempts to develop super-paramagnetic nanocomposite structure which have both magnetic and biocompatibility. With magnetic composite structure, nano-composite structure could be applied to bio-labeling, a specific tissue target detection and drug treatment. The author prepares Fe3O4 nanoparticles by chemical deposition. The diameter of the particle is about 20 nm, and is coated by CSALG complex membrane. Finally, the prepared nanocomposite structure undergone conjugating reaction with different types of ODNs are mixed in culturecell, so that they are linked together through the hybridization between different types of ODNs.
Keywords :
biochemistry; biomagnetism; biomedical materials; iron compounds; magnetic particles; nanobiotechnology; nanocomposites; nanofabrication; nanoparticles; superparamagnetism; Fe3O4; bio-labeling; chemical deposition; conjugating reaction; drug treatment; hybridization; superparamagnetic nanocomposite structure; tissue target detection; Biomembranes; Chemical technology; DNA; Iron; Magnetic cores; Mechanical engineering; Nanobioscience; Nanoparticles; Nanostructures; Surface morphology;
Conference_Titel :
Nanoelectronics Conference (INEC), 2010 3rd International
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-3543-2
Electronic_ISBN :
978-1-4244-3544-9
DOI :
10.1109/INEC.2010.5425168
