Title :
A study on the preparation and characterization of plasmid DNA and drug-contained magnetic nano-liposomes for the treatment of tumor
Author :
Wang, Zi-yu ; Wang, Li ; Zhang, Dong-sheng
Author_Institution :
Sch. of Med., Southeast Univ., Nanjing, China
Abstract :
To explore the preparation and characters of a novel nanosized magnetic liposome that contained PEI-As2O3/Mn0.5Zn0.5Fe2O4 (PEI- As2O3/MZF) complex. Experimental results suggest that PEI-As2O3/MZF magnetic nanoliposome is a kind of appropriate material which has multiple effects for tumor thermotherapy, gene therapy and chemotherapy.
Keywords :
DNA; arsenic compounds; biomembranes; cancer; cellular biophysics; drug delivery systems; gene therapy; lipid bilayers; manganese compounds; nanobiotechnology; tumours; zinc compounds; As2O3-Mn0.5Zn0.5Fe2O4; chemotherapy; drug-contained magnetic nanoliposomes; gene therapy; plasmid DNA; tumor thermotherapy; tumor treatment; DNA; Fluorescence; Gene therapy; Hyperthermia; Magnetic materials; Medical treatment; Nanoparticles; Neoplasms; Scanning electron microscopy; Transmission electron microscopy;
Conference_Titel :
Nanoelectronics Conference (INEC), 2010 3rd International
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-3543-2
Electronic_ISBN :
978-1-4244-3544-9
DOI :
10.1109/INEC.2010.5425178