Title :
Study on Purification of Used Oxygen-18 Water in Preparation of Positron with Cyclotron
Author :
Sun, Li-Quan ; Kasamatsu, Shingo ; Furukawa, Takako ; Fujibayashi, Yasuhisa
Author_Institution :
Sch. of Life Sci. & Technol., Beijing Inst. of Technol., Beijing
Abstract :
A novel method for recovering used O-18 water in [18F]FDG synthesis was developed. Base on the properties of anhydrous salt and salt with crystal water, anhydrous potassium fluoride and sodium sulfide were used to accomplish purification of used O-18 water. With the self-assembled instruments, the contaminants of methanol, ethanol and acetonitrile were decreased from 103 ppm, 496 ppm, 571 ppm to less than 32 ppm, 63 ppm, 50 ppm for methanol, ethanol and acetonitrile, respectively. The no-oxygen salt avoided to induce new oxygen-16 contaminants. Recovered O-18 water was used in radiotracer synthesis and gave similar radiochemical yield to new O-18 water.
Keywords :
biomedical equipment; cyclotrons; organic compounds; positron sources; potassium compounds; recycling; sodium compounds; water; water treatment; FDG synthesis; H2 18O; KS; NaS; acetonitrile; anhydrous potassium fluoride; anhydrous salt; anhydrous sodium sulfide; crystal water; cyclotron; methanol; no-oxygen salt; oxygen-18; positron; water purification; Biomedical imaging; Cyclotrons; Ethanol; Instruments; Medical diagnostic imaging; Methanol; Nuclear medicine; Positron emission tomography; Purification; Water conservation;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.1052
