Title :
Three-dimensional reconstruction of the cochlea
Author :
Brown, Carl S. ; Nelson, Alan C. ; Spelman, Francis A.
Author_Institution :
Center for Bioeng., Washington Univ., Seattle, WA, USA
Abstract :
Optical projections of a stained, intact guinea pig cochlea are reconstructed from 36 projection images, spaced every 5° around a semicircle, a three-dimensional image is computed within a cube of dimensions 256×256×256 pixels. Acquisition of data about a single tilt axis allows the 3-D reconstruction problem to be simplified to the reconstruction of multiple 2-D slices from 1-D projections. The resolution of the reconstruction matrix is approximately 15 μm3 per volume element. Various anatomical features are recognizable, including the scalae, the basilar membrane, the round and oval windows, and the modiolus
Keywords :
biological techniques and instruments; ear; 3D cochlear reconstruction; 3D image; anatomical features; basilar membrane; guinea pig; inner ear; modiolus; optical projections; oval window; projection images; round window; scalae; tilt axis; volume element; Biology computing; Biomedical engineering; Biomedical optical imaging; Computed tomography; Image reconstruction; Image resolution; Impedance; Optical distortion; Optical refraction; Optical sensors;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95861
