Three-dimensional reconstruction of the cochlea

Author

Brown, Carl S. ; Nelson, Alan C. ; Spelman, Francis A.

Author_Institution

Center for Bioeng., Washington Univ., Seattle, WA, USA

fYear

1989

Firstpage

536

Abstract

Optical projections of a stained, intact guinea pig cochlea are reconstructed from 36 projection images, spaced every 5° around a semicircle, a three-dimensional image is computed within a cube of dimensions 256×256×256 pixels. Acquisition of data about a single tilt axis allows the 3-D reconstruction problem to be simplified to the reconstruction of multiple 2-D slices from 1-D projections. The resolution of the reconstruction matrix is approximately 15 μm³ per volume element. Various anatomical features are recognizable, including the scalae, the basilar membrane, the round and oval windows, and the modiolus

Keywords

biological techniques and instruments; ear; 3D cochlear reconstruction; 3D image; anatomical features; basilar membrane; guinea pig; inner ear; modiolus; optical projections; oval window; projection images; round window; scalae; tilt axis; volume element; Biology computing; Biomedical engineering; Biomedical optical imaging; Computed tomography; Image reconstruction; Image resolution; Impedance; Optical distortion; Optical refraction; Optical sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in

Conference_Location

Seattle, WA

Type

conf

DOI

10.1109/IEMBS.1989.95861

Filename

95861