Title :
Functional enrichment analysis of miR-203 apoptosis-implicated target genes
Author_Institution :
FCM, Multimedia Univ., Cyberjaya, Malaysia
Abstract :
MicroRNAs are non-coding RNA molecules that regulate the protein coding messenger RNA genes. The understanding of microRNA-RNA binding pair is important in molecular biology and molecular therapy. In this study, functional enrichment analysis was employed to study the miR-203 target genes which are implicated in apoptosis. The obtained results will improve the understanding of the pathogenic regulatory mechanism of miR-203.
Keywords :
RNA; biological techniques; cellular biophysics; genetics; molecular biophysics; patient treatment; functional enrichment analysis; messenger RNA genes; miR-203 apoptosis implicated target genes; microRNA-RNA binding pair; molecular biology; molecular therapy; noncoding RNA molecules; pathogenic regulatory mechanism; protein coding mRNA genes; Cancer; Computational modeling; Diseases; Humans; Proteins; RNA; Tumors; MicroRNA; functional enrichment analysis; mRNA; miR-203;
Conference_Titel :
Biomedical Engineering (ICoBE), 2012 International Conference on
Conference_Location :
Penang
Print_ISBN :
978-1-4577-1990-5
DOI :
10.1109/ICoBE.2012.6179036
