Title :
Separation of diffusion and perfusion in the brain of a rat by MRI
Author :
Avram, H.E. ; Chen, J.-H.
Author_Institution :
Diasonics MRI, San Francisco, CO, USA
Abstract :
The implementation of a magnetic resonance imaging pulse sequence that is capable of giving true diffusion images is reported. The approach is based on the fact that diffusion processes are not reversible but that perfusion processes are. It uses a flow-compensated pulse sequence that is capable of rephasing the moving spins at the point of the spin echo. At the same time it provides an attenuation of the echo due to spin diffusion only on the order of 40%
Keywords :
biodiffusion; biological techniques and instruments; biomedical NMR; biorheology; blood; brain; echo attenuation; flow-compensated pulse sequence; magnetic resonance imaging pulse sequence; moving spins rephasing; rat brain diffusion; rat brain perfusion; Attenuation; Biological tissues; Biomedical imaging; Diffusion processes; Engineering in medicine and biology; Imaging phantoms; Magnetic fields; Magnetic resonance imaging; Sequences; Societies;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95891
