DocumentCode
1691847
Title
A preliminary work on evolutionary identification of protein variants and new proteins on grids
Author
Boisson, Jean-Charles ; Jourdan, Laetitia ; Talbi, El-Ghazali ; Rolando, Christian
Author_Institution
LIFL/INRIA Futurs, Lille I Univ., Villeneuve d´´Ascq, France
Volume
2
fYear
2006
Abstract
Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants. In this paper an evolutionary approach is proposed to discover new proteins or protein variants thanks a "de novo sequencing" method. This approach has been experimented on a specific grid called Grid5000 with simulated spectra and also real spectra.
Keywords
biological techniques; biology computing; evolutionary computation; grid computing; identification; proteins; Grid5000; de novo sequencing method; evolutionary identification; experimental mass spectrum; protein variant; Amino acids; Biological system modeling; Cells (biology); Chemicals; Databases; Mass spectroscopy; Peptides; Proteins; Proteomics; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Advanced Information Networking and Applications, 2006. AINA 2006. 20th International Conference on
ISSN
1550-445X
Print_ISBN
0-7695-2466-4
Type
conf
DOI
10.1109/AINA.2006.48
Filename
1620442
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