Title :
Micro-CT characterization of fusing extruded PCL scaffolds
Author :
Darling, A. ; Shor, L. ; Khalil, S. ; Wang, F. ; Güçeri, S. ; Sun, W.
Author_Institution :
Dept. of Mech. Eng. & Mech., Drexel Univ., Philadelphia, PA, USA
Abstract :
Micro-CT enables 3D characterization of the salient features of polymer scaffolds for tissue engineering applications. This paper presents our study on using micro-CT to evaluate the structural formability and the morphologies of PCL scaffolds fabricated by a Precision Extruding Deposition process. Results of as-fabricated scaffolds, with different processing parameters and micro-architectures were examined through micro-CT at 19.1 micron resolution. 2D analyses and 3D reconstructions of core regions of the sample scaffolds were performed. These results illustrate that qualitative and quantitative analysis of polymer scaffolds is possible through micro-CT and 3D reconstruction techniques.
Keywords :
biological tissues; biomedical materials; computerised tomography; extrusion; image reconstruction; medical image processing; polymers; 3D reconstruction techniques; core regions; extruded PCL scaffolds fusion; micro-CT characterization; polymer scaffolds; processing parameters; sample scaffolds; tissue engineering; Fabrication; Image analysis; Image reconstruction; Mechanical factors; Microarchitecture; Morphology; Polymers; Sun; Testing; Tissue engineering;
Conference_Titel :
Bioengineering Conference, 2003 IEEE 29th Annual, Proceedings of
Print_ISBN :
0-7803-7767-2
DOI :
10.1109/NEBC.2003.1216044
