Title :
Asymptotic homogenization based process for characterization of tissue scaffold
Author :
Fang, Z. ; Yan, C. ; Sun, W. ; Shokoufandeh, A. ; Regli, B.
Author_Institution :
Dept. of Mech. Eng. & Mech., Drexel Univ., Philadelphia, PA, USA
Abstract :
An asymptotic homogenization based process to characterize the effective mechanical properties of tissue scaffolds is presented. The process uses the concept of a composite unit cell to model heterogeneous tissue structures. By using a 3D asymptotic homogenization model, the effective mechanical properties of the designed tissue scaffolds can be determined. The process of the homogenization and the application of the model to scaffolds with different pore geometries and internal architectures are presented.
Keywords :
Poisson ratio; Young´s modulus; biological tissues; biomechanics; biomedical materials; biomimetics; calcium compounds; elastic constants; physiological models; polymer blends; polymers; porosity; shear modulus; 3D asymptotic homogenization model; Possion ratio; Young modulus; asymptotic homogenization based process; composite unit cell; effective mechanical properties; heterogeneous tissue structures; homogenization; hydroxyapatite; internal architectures; polycaprolactone; polylactic acid polyglycolic acid copolymer; pore geometries; shear modulus; tissue scaffold characterization; Computer science; Design automation; Geometry; Mechanical engineering; Mechanical factors; Predictive models; Regeneration engineering; Shape; Solid modeling; Tissue engineering;
Conference_Titel :
Bioengineering Conference, 2003 IEEE 29th Annual, Proceedings of
Print_ISBN :
0-7803-7767-2
DOI :
10.1109/NEBC.2003.1216076
