Title :
Dextran-based hydrogels for in-situ delivery of gallium-containing bioactive glasses
Author :
Keenan, T.J. ; Wren, A.W. ; Hall, Mark M.
Author_Institution :
Kazuo Inamori Sch. of Eng., Alfred Univ., Alfred, NY, USA
Abstract :
The overall goal of this project is to synthesize a degradable polymer hydrogel, which has the ability to act as a scaffold upon which therapeutic materials, particularly, Ga-containing bioactive glasses, can be seeded, while also allowing the ionic dissolution products of the glasses to interact with host tissues and fluids within the local environment.
Keywords :
biodegradable materials; biological fluid dynamics; biomedical materials; dissolving; drug delivery systems; gallium compounds; glass; hydrogels; materials preparation; degradable polymer hydrogel; dextran-based hydrogels; fluids; gallium-containing bioactive glasses; host tissues; in-situ delivery; ionic dissolution products; local environment; scaffold; therapeutic materials; Bones; Educational institutions; Glass; Polymers; Tumors; pH measurement; hydrogel; polymer;
Conference_Titel :
Bioengineering Conference (NEBEC), 2014 40th Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBEC.2014.6972834
