Title :
Poly(vinyl alcohol)-gelatin interpenetrating network hydrogels for tissue engineering applications
Author :
Miller, Emily J. ; Oldinski, Rachael A.
Author_Institution :
Mech. Eng. Program, Univ. of Vermont, Burlington, VT, USA
Abstract :
Erosion of articular cartilage results in subsequent destruction of subchondral bone, generating an osteochondral defect. Osteochondral tissue engineering would benefit from the use of multi-phasic biomimetic scaffolds to promote simultaneous regeneration of articular cartilage and subchondral bone.
Keywords :
bio-inspired materials; biomechanics; biomimetics; bone; composite materials; gelatin; hydrogels; materials preparation; medical disorders; polymer blends; tissue engineering; articular cartilage erosion; articular cartilage regeneration; multiphasic biomimetic scaffold; osteochondral defect; osteochondral tissue engineering; poly(vinyl alcohol)-gelatin interpenetrating network hydrogel; simultaneous cartilage-bone regeneration; subchondral bone destruction; subchondral bone regeneration; tissue engineering application; Bones; Diseases; Educational institutions; Mechanical engineering; Polymers; Scanning electron microscopy; Tissue engineering;
Conference_Titel :
Bioengineering Conference (NEBEC), 2014 40th Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBEC.2014.6972877