Title :
Controlled release of proteins with gel microparticles
Author :
Rios, J.L. ; Gongcheng Lu ; Seo, Na Eun ; Lambert, Tamara ; Putnam, David
Author_Institution :
Dept. of Biomed. Eng., Cornell Univ. Ithaca, Ithaca, NY, USA
Abstract :
Protein therapeutics are playing an ever increasing role in disease treatment; however, their controlled release remains challenging. In this study a series of microgels with varying crosslinking densities was synthesized, characterized and evaluated for their potential as controlled release protein delivery devices.
Keywords :
biomedical materials; diseases; drug delivery systems; materials preparation; polymer gels; proteins; controlled release protein delivery devices; crosslinking densities; disease treatment; gel microparticles; microgels; protein therapeutics; Chemicals; Drug delivery; Drugs; Loading; Polymers; Proteins; Shape; controlled release; drug delivery; protein therapeutics;
Conference_Titel :
Bioengineering Conference (NEBEC), 2014 40th Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBEC.2014.6972919
