Title :
Bone morphogenetic factor peptide functionalized rosette nanotubes for orthopedic applications
Author :
Sun, Lifeng ; Webster, Thomas J. ; Mi, Guangcan ; Alsbaiee, Alaaeddin ; Hemraz, Usha D. ; Cho, Jae-Young ; Beingessner, Rachel L. ; Fenniri, Hicham
Author_Institution :
Dept. of Chem. Eng., Northeastern Univ., Boston, MA, USA
Abstract :
Bone morphogenetic factors are important cytokines involved in skeletal development and bone remodeling. In this study, bone morphogenetic protein 7 peptides were functionalized on rosette nanotubes to promote bone cell adhesion and proliferation for orthopedic tissue engineering applications.
Keywords :
adhesion; biomechanics; biomedical materials; bone; cellular biophysics; nanomedicine; nanotubes; orthopaedics; proteins; tissue engineering; bone cell adhesion; bone cell proliferation; bone morphogenetic factor peptide functionalized rosette nanotubes; bone morphogenetic protein 7 peptides; bone remodeling; cytokines; orthopedic applications; orthopedic tissue engineering applications; skeletal development; Bones; Educational institutions; Fibroblasts; Nanotubes; Peptides; Protein engineering; Proteins; Bone morphogenetic proteins; bone regeneration; rosette nanotubes; self-assembling;
Conference_Titel :
Bioengineering Conference (NEBEC), 2014 40th Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBEC.2014.6972949
