Title :
A low-field P-31 NMR spectrometer to measure bone mineral in the human wrist
Author :
Battocletti, Joseph H. ; Myers, Thomas J. ; Scheidt, Robert
Author_Institution :
Dept. of Neurosurg., Med. Coll. of Wisconsin, Milwaukee, WI, USA
Abstract :
Nuclear magnetic resonance phosphorus spectroscopy (NMRS) is a method of measuring the mineral content of bone as a diagnostic tool for osteoporosis. A description is given of the design and construction of a low-field spectrometer for the human wrist. It uses a small-size permanent magnet of neodymium-iron-boron. The questions of whether a low-field spectrometer is sensitive enough to measure the phosphorus mineral content of bone and to what extent the phosphorus in soft tissue affects the measurement of bone mass are discussed
Keywords :
biomedical NMR; biomedical equipment; bone; patient diagnosis; Nd-Fe-B; bone mineral; construction; design; diagnostic tool; human wrist; low field 31P NMR spectrometer; mineral content; osteoporosis; small-size permanent magnet; Biological tissues; Bones; Humans; Mass spectroscopy; Minerals; Nuclear magnetic resonance; Nuclear measurements; Osteoporosis; Permanent magnets; Wrist;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96013
