• DocumentCode
    1720953
  • Title

    Simulation of microimages emitted by virtual array of testing oligonucleotides

  • Author

    Cysewska-Sobusiak, Anna ; Boltrukiewicz, Michal

  • Author_Institution
    Inst. of Electron. & Telecommun., Tech. Univ. Poznan, Poland
  • fYear
    2002
  • fDate
    6/24/1905 12:00:00 AM
  • Firstpage
    100
  • Lastpage
    104
  • Abstract
    This paper is concerned with utilization of virtual reality in biomeasurements. Presented questions have focused on predicting changes in the virtual optical response as a result of simulated changes in a considered DNA sequence composition. Relationships between thermodynamic and optical properties of a given sequence are taken in considering a light-directed library of testing oligonucleotides. The oligonucleotides embedded in the library volume make the array of short known sequences that are assumed as the testers. Simulated microimages entitled by a virtual array correspond to the sites where hybridization process is performed as a result of the DNA sequence base pairing characteristics. Presented simulation refers to changes in fluorescence signals to be sensed from the lighting array made by pixels, which intensities depend on parameters of the objects located in particular array sites.
  • Keywords
    DNA; biological techniques; biology computing; fluorescence; molecular biophysics; optical arrays; virtual reality; DNA sequence composition; fluorescence signals changes; microimages simulation; oligonucleotides testing; optical properties; short known sequences array; simulated changes; thermodynamic properties; virtual array; virtual optical response; Biomedical optical imaging; DNA; Libraries; Optical arrays; Optical sensors; Predictive models; Sequences; Stimulated emission; Testing; Virtual reality;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Virtual and Intelligent Measurement Systems, 2002. VIMS '02. 2002 IEEE International Symposium on
  • Print_ISBN
    0-7803-7344-8
  • Type

    conf

  • DOI
    10.1109/VIMS.2002.1009365
  • Filename
    1009365