Title :
Feature genes selection of adult ALL microarray data with affinity propagation clustering
Author :
Chen-Chia Chuang ; Yan-Cheng Li ; Jin-Tsong Jeng ; Chih-Kai Chang ; Zhi-Qian Wang
Author_Institution :
Dept. of Electr. Eng., Nat. Ilan Univ., Ilan, Taiwan
Abstract :
Microarray data analysis approach has been became a widely used tool for disease detection. It uses tens of thousands of genes as input dimension that would be a huge computational problem for data analysis. In this paper, we proposed to apply affinity propagation (AP) clustering for feature genes selection of adult acute Lymphoblastic Leukemias (ALL) microarray data. That is, feature genes can be finding out according to the adjustable the number of cluster in AP clustering. AP Clustering is a new grouping method by passing messages between data points, AP clustering can to reduce dimension on each sample without known the number of cluster in advance. Finally, these results under the specific genes with AP clustering can provide learning in classification and prediction.
Keywords :
blood; cancer; cellular biophysics; classification; data analysis; feature extraction; feature selection; genetics; lab-on-a-chip; learning (artificial intelligence); medical diagnostic computing; patient diagnosis; pattern clustering; AP clustering; adult ALL microarray data analysis; adult acute lymphoblastic leukemia microarray data; affinity propagation clustering; classification learning; cluster number; computational problem; data point message passing; disease detection; feature gene selection; grouping method; input dimension; prediction learning; sample dimension reduction; Algorithm design and analysis; Clustering algorithms; Data analysis; Diseases; Ranking (statistics); Regulators; Statistical analysis;
Conference_Titel :
Consumer Electronics - Taiwan (ICCE-TW), 2015 IEEE International Conference on
Conference_Location :
Taipei
DOI :
10.1109/ICCE-TW.2015.7216871