Title :
Magnetic actuated MOEMS resonant biosensor array
Author :
Timurdogan, Erman ; Nargul, Sezin ; Kavakli, Halil ; Alaca, Erdem ; Urey, Hakan
Author_Institution :
Koc Univ., Istanbul, Turkey
Abstract :
A biosensor platform is utilized in liquid for detection of His protein. T-shaped thin film nickel cantilevers are actuated magnetically using self-oscillation principle and the sensing is based on embedded diffraction gratings on the cantilevers with interferometric sensitivity. Experiments are performed in a custom 1ml liquid chamber and 5.7ng/ml detection sensitivity is demonstrated. Method is label-free, robust and allows multiplexing. It also doesn´t require any electrical connections to the MEMS sensor chip. Therefore, it is suitable for real-time multi analyte screening using a disposable chip in a portable device.
Keywords :
bioMEMS; biosensors; cantilevers; diffraction gratings; electromagnetic actuators; metallic thin films; micro-optomechanical devices; molecular biophysics; nickel; optical sensors; proteins; MEMS sensor chip; biosensor platform; disposable chip; embedded diffraction gratings; interferometric sensitivity; liquid chamber; liquid detection; magnetic actuated MOEMS resonant biosensor array; portable device; protein; real-time multianalyte screening; self-oscillation principle; thin film nickel cantilevers; Arrays; Biomedical optical imaging; Biosensors; Frequency measurement; Magnetic liquids; Optical device fabrication; Optical sensors;
Conference_Titel :
Optical MEMS and Nanophotonics (OPT MEMS), 2010 International Conference on
Conference_Location :
Sapporo
Print_ISBN :
978-1-4244-8926-8
Electronic_ISBN :
978-1-4244-8925-1
DOI :
10.1109/OMEMS.2010.5672211