Title :
A smart sensor for biomedical applications
Author :
Sansen, W. ; Claes, A. ; De Wachter, D. ; Callewaert, L. ; Lambrechts, M.
Author_Institution :
Dept. of Elektrotech., Katholieke Univ., Leuven, Heverlee, Belgium
Abstract :
A monolithic smart sensor that can be used for voltammetric measurements of glucose or oxygen concentrations has been developed. It consists of a planar voltammetric sensor, a CMOS interface circuit and a temperature sensor. The interface circuit and the temperature sensor are realized in a standard CMOS process. The sensor-specific layers are added afterward to the same chip, using CMOS-compatible sensor technology developed for this purpose. Two versions of this smart sensor have been realized. A two-electrode configuration with an Au working electrode has been implemented for the measurement of pO2. A three-electrode configuration with a Pt working electrode can measure glucose when an additional glucose oxidase membrane is applied to the electrodes. The interface circuit can apply voltages from +1 V to -1 V to the sensor and can handle sensor currents from 30 nA full scale to 1 μA full scale with a ±2.5-V supply voltage. The temperature sensor has a sensitivity of 154 μV/K. The dimensions of the smart sensor are 0.75 mm by 5 mm
Keywords :
biomedical electronics; biosensors; -2.5 to 2.5 V; 1 muA; 2-electrode configuration; 30 nA; CMOS interface circuit; O2 concentration measurement; biomedical smart sensor; interface circuit; monolithic smart sensor; planar voltammetric sensor; sensor-specific layers; temperature sensor; voltammetric measurements; Biomedical measurements; Biosensors; CMOS process; Circuits; Electrodes; Intelligent sensors; Semiconductor device measurement; Sugar; Temperature sensors; Voltage;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96099
