• DocumentCode
    1741195
  • Title

    Modeling and realizing biological mechanisms on FPGA chip

  • Author

    Botros, Nazeih M.

  • Author_Institution
    Dept. of Electr. Eng., Southern Illinois Univ., Carbondale, IL, USA
  • Volume
    3
  • fYear
    2000
  • fDate
    2000
  • Firstpage
    1921
  • Abstract
    We explore the feasibility of the study by considering a simplified blood-pressure regulation mechanism done by the kidney. The concept of this mechanism is illustrated as follows. If the blood pressure (bp) decreases, the activity of the sympathetic neural (sn)system increases, the renal blood flow (rf) decreases, the sodium excretion (Na+) decreases which leads to an increase (stabilization) in the blood pressure. A VHDL-behavioral modeling of the mechanism is shown below. In the modeling, the normal value of the blood pressure is assumed to be 17 units (any other value could have been assumed). To show that sn increases if bp decreases, we use a simple formula sn=(constant1-bp)+constant2. The simulation shows that the mechanism is working successfully. The simulation has been downloaded into a Xilinx FPGA XC4005. The chip behaves identically to the simulation
  • Keywords
    field programmable gate arrays; haemodynamics; hardware description languages; kidney; medical computing; physiological models; FPGA chip; VHDL-behavioral modeling; biological mechanisms modeling; kidney; renal blood flow; simplified blood-pressure regulation mechanism; sodium excretion; sympathetic neural system activity; Biological system modeling; Blood flow; Blood pressure; Field programmable gate arrays; Libraries; PROM;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
  • Conference_Location
    Chicago, IL
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-6465-1
  • Type

    conf

  • DOI
    10.1109/IEMBS.2000.900467
  • Filename
    900467