Title :
Calculated electrons energy levels in gadolinium atoms and utilization of the Gd157(n,γ)Gd158 reaction as a source of Auger electrons for tumor cells killing
Author :
Shani, Gad ; Laster, Brenda ; Rozin, Semion ; Miloshevsky, G.V. ; Tolkach, V.I.
Author_Institution :
Dept. of Nucl. Eng., Ben-Gurion Univ. of the Negev, Beer-Sheva, Israel
Abstract :
It was found that the energy deposited in the cell from each 10B(n,α) reaction is 2.3 MeV. This represents the total kinetic energy of the alpha particle and the Li ion. The energy deposited in the cell from each 157Gd(n,γ)158Gd reaction is 0.045 MeV, due to the Auger electrons. It was found that ~6 10B(n,α) 7Li reactions were needed at dose of 3.3 MW × Minutes to damage the cells to the 10% level of survival. (The dose is expressed in MW-Min units, i.e. reactor power multiplied by irradiation time in minutes, to avoid using various unknown values of RBE.) Because of the high Gd(n,γ) cross section, this same level of survival was obtained at 1.8 MW-Min, with 68 157Gd(n,γ)158Gd reactions
Keywords :
Auger effect; cellular effects of radiation; gadolinium; neutron-nucleus reactions; tumours; 0.045 MeV; 2.3 MeV; Auger electrons source; B; Gd; Gd157(n,γ)Gd158 reaction; Li; calculated electrons energy levels; cellular radiobiology; gadolinium atoms; reactor power; survival level; tumor cells killing; Atomic measurements; Electron emission; Energy states; Heat transfer; Kinetic theory; Photovoltaic effects; Power engineering and energy; Radioactive decay; Tumors; Wave functions;
Conference_Titel :
Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-6465-1
DOI :
10.1109/IEMBS.2000.900688
