Title :
Transition from ventricular tachycardia to ventricular fibrillation as function of tissue characteristics computer model
Author :
Fenton, Flavio H. ; Karma, Alain ; Hastings, Harold M. ; Evans, Steven J.
Author_Institution :
Dept. of Math., Hofstra Univ., Hempstead, NY, USA
Abstract :
A simplified quantitative ionic model of cardiac action potential, which reproduces accurate restitution curves, is used in conjunction with global tissue characteristics such as rotational cell anisotropy and periodic boundaries to study the transition from ventricular tachycardia (VT) to ventricular fibrillation (VF). The authors give an explanation for the experimental observation that there is a minimum tissue mass required for this transition to occur
Keywords :
cellular biophysics; digital simulation; electrocardiography; medical computing; physiological models; accurate restitution curves; cardiac action potential; minimum tissue mass; periodic boundaries; rotational cell anisotropy; simplified quantitative ionic model; tissue characteristics computer model; ventricular fibrillation; ventricular tachycardia; Anisotropic magnetoresistance; Cardiac tissue; Computer simulation; Fibrillation; Frequency; Heart beat; Myocardium; Spatiotemporal phenomena; Spirals; Voltage;
Conference_Titel :
Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-6465-1
DOI :
10.1109/IEMBS.2000.900757
