Title :
Beam-orientation optimisation of IMRT: clinical application to parotid gland tumours
Author :
Rowbottom, Carl ; Nutting, Chris ; Webb, S.
Author_Institution :
NOMOS Corp., Sewickley, PA, USA
Abstract :
The potential of IMRT to reduce toxicity was investigated. Initially, a treatment plan was set-up on the CORVUS1 inverse treatment planning system using nine equi-spaced beams. The goal of the inverse plan was to reduce the dose to the cochlea and the oral cavity compared to the conformal wedged pair technique. The plan reduced the dose to the cochlea and to a lesser extent reduced the volume of the oral cavity receiving high-dose, and also improved the PTV homogeneity. Unfortunately, compared to the conformal wedged pair technique, the IMRT plan greatly increased the dose to the contralateral parotid gland with 73% of the OAR receiving dose in excess of 6 Gy
Keywords :
biological organs; dosimetry; radiation therapy; tumours; 6 gray; beam-orientation optimisation; clinical application; cochlea dose reduction; conformal wedged pair technique; contralateral parotid gland; equispaced beams; homogeneity improvement; intensity modulated radiotherapy; inverse plan; oral cavity; parotid gland tumours; toxicity reduction; Cost function; Deafness; Glands; Mouth; Optimization methods; Size control; Spinal cord; Surgery; Tumors;
Conference_Titel :
Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-6465-1
DOI :
10.1109/IEMBS.2000.900778