Title :
Development of fibre bundle probe for coherent anti-stokes Raman scattering microendoscopy
Author :
Zhengfan Liu ; Zhiyong Wang ; Satira, Zachary A. ; Xu Chen ; Shufen Chen ; Jianguo Xin ; Wong, Stephen T. C.
Author_Institution :
Sch. of Optoelectron., Beijing Inst. of Technol., Beijing, China
Abstract :
A fibre bundle has been developed for coherent anti-Stokes Raman scattering (CARS) microendoscopy. The polarisation scheme was employed to suppress the four-wave mixing (FWM) effect in the fibre. High collection efficiency of epi-CARS signals and isolation of excitation lasers are achieved. Epi-CARS and epi-FWM images were compared in different polarisation schemes. The use of a broadband dual wavelength waveplate offers spectroscopic imaging capability to the system, which was shown by using ex vivo imaging mouse tissues.
Keywords :
biological tissues; biomedical optical imaging; coherent antiStokes Raman scattering; endoscopes; fibre optic sensors; multiwave mixing; optical fibre polarisation; probes; CARS; FWM; broadband dual wavelength waveplate; coherent antiStokes Raman scattering microendoscopy; epi-CARS; epi-FWM; ex vivo imaging; fibre bundle probe; fibre polarisation; four-wave mixing suppression; mouse tissues; spectroscopic imaging;
Journal_Title :
Electronics Letters
DOI :
10.1049/el.2013.0220
