Double-layer silver nanoparticle arrays-based localised surface plasmon resonance optical sensor for sensitive detection of concanavalin A

Author

Weixiang Ye ; Wei Zhang ; Cheng Wang ; Wenbin Li ; Huawei Yu ; Guohua Liu

Author_Institution

Coll. of Electron. Inf. & Opt. Eng., Nankai Univ., Tianjin, China

Volume

9

Issue

4

fYear

2014

fDate

41730

Firstpage

294

Lastpage

296

Abstract

A localised surface plasmon resonance (LSPR) optical sensor with double-layer silver nanoparticle (Ag NP) arrays has been developed for the sensitive detection of concanavalin A (ConA). Based on the principle of carbohydrate-protein interactions, double-layer dextran capped Ag NP arrays were initially constructed. The increase of adsorption apparent mass and LSPR coupling between the two Ag NP arrays can effectively enhance the LSPR spectral shift response. Compared with the single-layer Ag NP arrays configuration, the double-layer Ag NP arrays configuration improves the limitation of detection of ConA concentration from 3.42 to ~1.14 μg/ml.

Keywords

adsorption; biosensors; molecular biophysics; nanoparticles; nanosensors; optical sensors; proteins; silver; spectral line shift; surface plasmon resonance; Ag; LSPR coupling; LSPR spectral shift response; adsorption apparent mass; carbohydrate-protein interactions; concanavalin A detection; double-layer dextran capped silver nanoparticle arrays; localised surface plasmon resonance; optical sensor;

fLanguage

English

Journal_Title

Micro & Nano Letters, IET

Publisher

iet

ISSN

1750-0443

Type

jour

DOI

10.1049/mnl.2013.0720

Filename

6808621