• DocumentCode
    1768269
  • Title

    Biosensor systems and applications in genomics, proteomics and metabolomics: A review

  • Author

    MacKay, Scott ; Jie Chen

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Univ. of Alberta, Edmonton, AB, Canada
  • fYear
    2014
  • fDate
    1-5 June 2014
  • Firstpage
    217
  • Lastpage
    220
  • Abstract
    This article provides a brief overview and background on current biosensor designs for applications in genomics, proteomics and metabolomics. As research continues in many different aspects of biosensor design, new and better ways to recognize and detect low concentrations of a wide variety of different biomolecules are being developed for various applications. Biosensors can offer a simpler, faster and cheaper alternative to the testing that is often required to collect the large amounts of data for genomic, proteomic and metabolomic sensing. Recognition elements such as DNA aptamers make detecting very different types of biomolecules in the same system possible, while the use of signal-enhancing nanoparticle probes and microfabricated sensor arrays make it possible to test for a large number of different target biomolecules quickly and effectively.
  • Keywords
    DNA; biosensors; genomics; microsensors; nanoparticles; nanosensors; proteomics; DNA aptamers; biomolecule detection; biosensor designs; biosensor systems; genomic sensing; metabolomic sensing; microfabricated sensor arrays; proteomic sensing; recognition elements; signal-enhancing nanoparticle probes; target biomolecules; Biosensors; DNA; Electrodes; Gold; Molecular biophysics; Nanoparticles; Target recognition; Antibody; Aptamer; Biosensor; Carbon nanotube; Electrochemical detection; Genomics; Mass based detection; Optical detection; Proteomics and Metabolomics; RNA/DNA; SELEX;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Circuits and Systems (ISCAS), 2014 IEEE International Symposium on
  • Conference_Location
    Melbourne VIC
  • Print_ISBN
    978-1-4799-3431-7
  • Type

    conf

  • DOI
    10.1109/ISCAS.2014.6865104
  • Filename
    6865104