Title :
Optical coherence imaging of hemodynamics, metabolism, and cell viability during brain injury
Author :
Srinivasan, V. ; Shau Poh Chong ; Merkle, Conrad William ; Radhakrishnan, Harsha ; Leahy, Conor
Author_Institution :
Biomed. Eng. Dept., Univ. of California Davis, Davis, CA, USA
Abstract :
Pre-clinical quantitative imaging endpoints have been challenging in mouse models of cerebrovascular disease. Here we present optical coherence imaging platforms that can quantify blood flow, capillary perfusion, cellular status, and oxygen extraction based on intrinsic scattering signatures.
Keywords :
biomedical optical imaging; brain; cellular biophysics; diseases; haemodynamics; haemorheology; injuries; light scattering; optical tomography; blood flow; brain injury; capillary perfusion; cell viability; cellular status; cerebrovascular disease; hemodynamics; intrinsic scattering; metabolism; mouse models; optical coherence imaging; oxygen extraction; preclinical quantitative imaging; Biomedical optical imaging; Coherence; Optical imaging; Optical pulses; Optical saturation; Optical scattering;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA
