Title :
A depth perturbation method for determining depth of fluorophore in tissue
Author :
Tuo Zhou ; Ando, Takehiro ; Hongen Liao ; Koyashi, Etsuko ; Sakuma, Ichiro
Author_Institution :
Dept. of Precision Eng., Univ. of Tokyo, Tokyo, Japan
Abstract :
Estimating bio-distribution of fluorophore in tissue is challenging. In this paper, we demonstrated that our depth perturbation method can accurately determine depth of fluorophore located in tissue as deep as 5.8 mm (in epi-illumination geometry) by phantom experiments.
Keywords :
biological tissues; biomedical optical imaging; optical tomography; perturbation theory; phantoms; biological tissue; depth perturbation method; epi-illumination geometry; fluorophore biodistribution; phantom; Educational institutions; Fluorescence; Laser beams; Optical imaging; Phantoms; Scattering;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA