Title :
Optimizing the surface enhanced Raman signal for accurate identification of DNA base pairs
Author :
Freeman, Lindsay ; Lin Pang ; Fainman, Yeshaiahu
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of California San Diego, La Jolla, CA, USA
Abstract :
DNA sequencing currently lacks optical based techniques such as Raman spectroscopy. We have identified previous issues that prevented sequencing with Raman measurements and proposed a solution for base pair identification via surface enhanced Raman spectroscopy.
Keywords :
DNA; molecular biophysics; molecular configurations; surface enhanced Raman scattering; DNA base pairs; DNA sequence; Raman measurements; optical-based techniques; surface enhanced Raman signal; surface enhanced Raman spectroscopy; Absorption; Charge transfer; DNA; Films; Raman scattering; Silver; Substrates;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA
