Title :
Photonic crystal based immunosensor for clinical diagnosis
Author :
Zecca, D. ; Qualtieri, A. ; Magno, G. ; Grande, M. ; Petruzzelli, V. ; Prieto-Simon, B. ; D´Orazio, A. ; De Vittorio, M. ; Voelcker, N.H. ; Stomeo, T.
Author_Institution :
Center for Bio-Mol. Nanotechnol., Ist. Italiano di Tecnol. (IIT), Arnesano, Italy
Abstract :
The progress in medical field has provided fast remedies for the most of diseases affecting today´s society. Now, the next step is to propose a fast way of diagnosis, avoiding long waiting time and expensive laboratory assays. Thanks to the recent research findings and progress in nano-technological fabrication techniques, new biosensors have been developed with the purpose to introduce portable and user-friendly instruments for medical analysis aimed to improve life quality and lower healthcare costs. In this work, we propose a proof-of-concept of an immunosensor based on a two-dimensional silicon nitride photonic crystal membrane able to efficiently detect the concentration of Interleukin-6 in a buffer solution.
Keywords :
biomedical equipment; biosensors; membranes; molecular biophysics; nanomedicine; nanosensors; photonic crystals; proteins; silicon compounds; Si3N4; biosensors; buffer solution; clinical diagnosis; diseases; health care; interleukin-6 concentration; medical analysis; medical field; nanotechnological fabrication techniques; photonic crystal based immunosensor; portable instruments; two-dimensional silicon nitride photonic crystal membrane; user-friendly instruments; Biomembranes; Biosensors; Fabrication; Immune system; Photonic crystals; Proteins; Silicon nitride; Immunosensor; Interleukin-6; Label-free sensor; Photonic crystal;
Conference_Titel :
Photonics Conference, 2014 Third Mediterranean
Conference_Location :
Trani
DOI :
10.1109/MePhoCo.2014.6866459