Title :
Self-assembled lipid nanoparticles for imaging disease
Author_Institution :
Oak Ridge Nat. Lab. Oak Ridge, Oak Ridge, TN, USA
Abstract :
Self-assembled nanoparticles composed of low-cost phospholipids unilamellar vesicles (ULVEs) were developed and functionalized with molecular targeting agents to target and image brain diseases.
Keywords :
biomedical MRI; brain; diseases; lipid bilayers; molecular biophysics; nanomedicine; nanoparticles; self-assembly; image brain diseases; low-cost phospholipid unilamellar vesicles; molecular targeting agents; self-assembled lipid nanoparticles; Diseases; Drugs; Lipidomics; Molecular imaging; Neutrons; Tumors; amyloid; biomembrane; disease component; imaging; lipids; magnetic resonance imaging; protein complexes; scattering; single-domain antibodies; small angle neutron scattering; tissue; unilamelar vesicles diffraction;
Conference_Titel :
Biomedical Science and Engineering Center Conference (BSEC), 2014 Annual Oak Ridge National Laboratory
Conference_Location :
Oak Ridge, TN
DOI :
10.1109/BSEC.2014.6867754
