Title :
Nanopore fluidic SERS
Author :
Chang Chen ; Yi Li ; Kerman, Sarp ; Neutens, Pieter ; Lagae, Liesbet ; Stakenborg, Tim ; Van Dorpe, Pol
Author_Institution :
Imec, Leuven, Belgium
Abstract :
We describe a technology combining nanopore fluidic with surface enhanced Raman spectroscopy (SERS) for real-time, single molecule detection. After optimization of both optical and device design, we can control the nanopore like a valve for molecule motions and detect a single nucleotide even at 10 ms.
Keywords :
nanofluidics; nanophotonics; nanoporous materials; surface enhanced Raman scattering; device design; molecule motions; nanopore fluidic SERS; optical design; real-time single molecule detection; single nucleotide; surface enhanced Raman spectroscopy; valve; Cavity resonators; DNA; Gold; Nanoscale devices; Plasmons; Raman scattering; Real-time systems;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA
