Characterization of the fourier spatial frequencies of time resolved laser speckle from interacting high density lipoprotein disks

Author

Russell, S. ; Nguyen, T.A. ; Torres, C.R. ; Bhagroo, S. ; Russell, M.J. ; Camara, H. ; Pogue, B.W. ; Alfano, R.R.

Author_Institution

Mech. Eng. Dept., City Coll. of New York, New York, NY, USA

fYear

2014

fDate

April 29 2014-May 2 2014

Firstpage

1328

Lastpage

1331

Abstract

Fourier spatial frequency analysis of 2-D laser speckle images was used to identify the interaction of high density lipoprotein (HDL) nanoparticles in aqueous suspension at different ionic strengths. The decorrelation function of a time series of laser speckle images was used to identify key spectral ranges of HDL samples, and characteristic frequencies were extracted. These families of frequencies can be used as unique identifiers of nanometer scale structure in particle suspensions.

Keywords

biomedical optical imaging; decorrelation; laser applications in medicine; molecular biophysics; nanomedicine; nanoparticles; proteins; suspensions; time series; 2-D laser speckle images; Fourier spatial frequency analysis; HDL nanoparticles; aqueous suspension; decorrelation function; high density lipoprotein disks; particle suspensions; time resolved laser speckle; time series; Aggregates; Decorrelation; Hardware design languages; Microscopy; Speckle; Suspensions; Time-frequency analysis; Multispectral and hyperspectral imaging; dynamic imaging; total variation;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on

Conference_Location

Beijing

Type

conf

DOI

10.1109/ISBI.2014.6868122

Filename

6868122