Measurement set-up for lab-on-a-chip fluorimetric detection

Author

Augustyniak, Izabela ; Kubicki, Wojciech ; Dziuban, Jan ; Lizanets, Danylo ; Matviykiv, Oleh ; Lobur, Mykhailo

Author_Institution

Fac. of Microsyst. Electron. & Photonics, Wroclaw Univ. of Technol., Wroclaw, Poland

fYear

2014

fDate

19-21 June 2014

Firstpage

85

Lastpage

88

Abstract

Fluorimetric detection is widely utilized in analytical applications including pathogen detection, clinical diagnosis and DNA analysis. This method combined with lab-on-a-chip (LOC) technique provides new class of miniature and ultrasensitive bioanalytical tools and therefore new solutions are being widely developed. We present new measurement set-up for lab-on-a-chip fluorimetric detection which consists of silicon-glass LOC microreactor, detection unit with CCD-sensor, semiconductor laser module and dedicated software. Unique image-processing algorithm provides real-time fluorescence signal analysis and databasing.

Keywords

CCD image sensors; DNA; image processing; lab-on-a-chip; semiconductor lasers; silicon; spectrochemical analysis; CCD-sensor; DNA analysis; clinical diagnosis; detection unit; image-processing algorithm; lab-on-a-chip fluorimetric detection; measurement set-up; pathogen detection; semiconductor laser module; silicon-glass LOC microreactor; Fluorescence; Lab-on-a-chip; Measurement by laser beam; Optical filters; Semiconductor device measurement; Software; Wavelength measurement; Laser Induced Fluorescence detection; lab-on-a-chip; software-based image conditioning;

fLanguage

English

Publisher

ieee

Conference_Titel

Mixed Design of Integrated Circuits & Systems (MIXDES), 2014 Proceedings of the 21st International Conference

Conference_Location

Lublin

Print_ISBN

978-83-63578-03-9

Type

conf

DOI

10.1109/MIXDES.2014.6872160

Filename

6872160