• DocumentCode
    1787361
  • Title

    Discovering Differentially Expressed Genes in Yeast Stress Data

  • Author

    Goncalves, Afonso ; Ong, Irene ; Lewis, Jeffrey A. ; Costa, V.S.

  • Author_Institution
    Dept. of Comput. Sci., Univ. do Porto, Porto, Portugal
  • fYear
    2014
  • fDate
    27-29 May 2014
  • Firstpage
    537
  • Lastpage
    538
  • Abstract
    Transcriptional regulation plays an important role in every cellular decision. Gaining an understanding of the dynamics that govern how a cell will respond to diverse environmental cues is difficult using intuition alone. We try to discover how genes interact when submitted to stress by exploring techniques of gene expression data analysis. We use several types of data, including high-throughput data. These results will help us recreate plausible regulatory networks by using a probabilistic logical model. Hence, network hypotheses can be generated from existing gene expression data for use by experimental biologists.
  • Keywords
    bioinformatics; cellular biophysics; data analysis; probability; bioinformatics; cellular decision; gene expression data analysis; high-throughput data; probabilistic logical model; transcriptional regulation; yeast stress data; Correlation; Electronic mail; Encoding; Gene expression; Heating; Stress; Bioinformatics; Data Analysis; Gene Regulation; Genomics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computer-Based Medical Systems (CBMS), 2014 IEEE 27th International Symposium on
  • Conference_Location
    New York, NY
  • Type

    conf

  • DOI
    10.1109/CBMS.2014.127
  • Filename
    6881963