Title :
An integrated device for simultaneously monitoring electrocorticography and cerebral blood flow in rat´s brain
Author :
Shihan Feng ; Zhen Chao ; Binlin Zhang ; Peng Miao
Author_Institution :
Sch. of Commun. & Inf. Eng., Shanghai Univ., Shanghai, China
Abstract :
Neurovascular coupling (NVC) is one of the essential mechanisms in brain activities. Both cerebral blood flow (CBF) and electrocorticography (ECoG) have been serving as the most important indicators of neurovascular coupling in system level. In this study, we developed an integrated device to realize laser speckle contrast imaging (LSCI) and ECoG recording simultaneously in rat´s brain. Using this new integrated system, an in-vivo animal experiment was conducted when the rat was anesthetic. Based on data analysis, beta oscillations in rat´s ECoG demonstrated an interesting synchronization with blood flow of major artery in the same hemisphere.
Keywords :
blood flow measurement; blood vessels; brain; data analysis; laser applications in medicine; neurophysiology; patient monitoring; CBF; ECoG recording; LSCI; NVC; beta oscillations; brain activities; cerebral blood flow monitoring; data analysis; electrocorticography monitoring; in-vivo animal experiment; integrated device; laser speckle contrast imaging; major artery; neurovascular coupling; rat brain; synchronization; system level; Animals; Blood flow; Couplings; Imaging; Lasers; Monitoring; Speckle; cerebral blood flow (CBF); electrocorticography ECoG; laser speckle contrast imaging (LSCI); neurovascular coupling (NVC);
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2014 7th International Conference on
Conference_Location :
Dalian
Print_ISBN :
978-1-4799-5837-5
DOI :
10.1109/BMEI.2014.7002738
