Author_Institution :
Sch. of Eng., Dept. of Electr. & Comput. Eng., New York Univ., New York, NY, USA
Abstract :
This work describes a method using sparse optimization for the detection of K-complex in sleep EEG. K-complex is an important feature in sleep stage identification, which is helpful to sleep disorder diagnostics process. In this work, a discrete-time sleep EEG signal Y ϵ RN is modeled as: Y=X1+X2+W, (1) where x1 is the baseline trend, X2 is composed of K-complexes, and w presents noise. More specifically, x1 is piecewise smooth comprising a lowpass signal component f, and a sparse order-K1 derivative component g1 i.e., x1 = f + g1. Further, x2 is assumed as a transient waveform with a negative wave followed by a positive wave, and modeled as a `wavelet´ (e.g. Fig. 1(b)). Moreover, x2 is modeled as the output of a high-pass filter, i.e., x2 = H2g2. In addition, we assume the order-K1 derivative of g1 is sparse, and we likewise assume the order-K2 derivative of g2 is sparse. In another word, g1 and g2 are sparse-derivative signals, where u1 = D1g1, and u2 = D2g2 are both sparse. Adopting the zero-phase filter design techniques discussed in Ref. [3], and the idea of morphological component analysis (MCA) [4], we formulate the optimization problem: {u1*, u2*} = arg min u1, u2 1/2|| H1y - A1-1B1u1 - A2-1B2u2||22 + λ1Σn ρ1([u1]n)+ λ2 Σnρ2([u2]n). (2) where P1 and P2 denote penalty functions. The high-pass filters are expressed as H1 = A1<- sub>-1B, H2= A2-1B, with B = B1D1 = B2D2. Using the solution from (2) we recover x1 and x2 by: x1 = Y - H1y + A1-1B1u1*, = x2=A2-1B2u2*. Problem (2) both decomposes the data y into x1 and X2, and performs denoising. It can be solved iteratively by majorization-minimization (MM) [2]. Further, the proposed algorithm is computationally efficient as it makes use of banded matrices. We use an asymmetric penalty function to capture the morphology of K-complex, and implement a simple detector by thresholding the local energy of X2. We test the proposed method by the public dataset collected in [1]. It achieves a better accuracy (F-measurement) than the result reported in [1]. An example is illustrated in Fig. 2.
Keywords :
electroencephalography; high-pass filters; low-pass filters; medical disorders; medical signal processing; minimisation; signal denoising; sleep; smoothing methods; waveform analysis; F-measurement; K-complex detection; K-complex morphology; asymmetric penalty function; banded matrices; data decomposition; denoising; discrete-time sleep EEG signal; high-pass filter; local energy thresholding; low-pass signal component; majorization-minimization; morphological component analysis; negative wave; order-K2 derivative; piecewise smoothing; positive wave; public dataset collection; simple detector; sleep disorder diagnostics; sleep stage identification; sparse optimization; sparse order-K1 derivative component; sparse-derivative signals; transient waveform; zero-phase filter design techniques; Brain modeling; Electroencephalography; Noise reduction; Optimization; Signal processing algorithms; Sleep; Transient analysis;