Diagnostics of radiation induced tissue damage and remodeling by laser scanning microscopy with second harmonic generation

Author

Maslennikova, A. ; Kochueva, M. ; Kuznetsov, S. ; Kiseleva, E. ; Kamensky, V. ; Ignatjeva, N. ; Zakharkina, O. ; Babak, K. ; Dudenkova, V.

Author_Institution

Nizhny Novgorod State Med. Acad., Nizhny Novgorod, Russia

fYear

2014

fDate

June 30 2014-July 4 2014

Firstpage

1

Lastpage

1

Abstract

Normal bladder mucosa has a high-contrast stratified structure with well-delineated epithelium, basal membrane and lamina propria. The urothelial cells form a smooth dense layer without connective tissue elements. Submucosal and muscle layers have a well expressed vessel´s network. Muscle fibers form bundles of an equal size in different directions. A small amount of connective tissue fibers form a scaffold of the tissue.

Keywords

biomembranes; cellular effects of radiation; laser applications in medicine; muscle; optical harmonic generation; optical microscopy; patient diagnosis; basal membrane; connective tissue fibers; high-contrast stratified structure; lamina propria; laser scanning microscopy; muscle fibers; muscle layers; normal bladder mucosa; radiation induced tissue damage diagnostics; second harmonic generation; submucosal layers; tissue scaffold; urothelial cells; vessel network; well-delineated epithelium; Medical diagnostic imaging; Muscles; Standards; bladder; collagen; gamma-irradiation; laser scanning microscopy; radiation induced fibrosis; rectum; second harmonic generation;

fLanguage

English

Publisher

ieee

Conference_Titel

Laser Optics, 2014 International Conference

Conference_Location

Saint Petersburg

Print_ISBN

978-1-4799-3884-1

Type

conf

DOI

10.1109/LO.2014.6886455

Filename

6886455