Title :
miRNA-720 regulates the stem cell phenotype and differentiation of human dental pulp-derived mesenchymal stromal cells
Author :
Hara, Emilio Satoshi ; Ono, M. ; Eguchi, Tohru ; Pham, Hai Thanh ; Tajima, Shinya ; Calderwood, Stuart K. ; Matsumoto, Tad ; Kuboki, Takuo
Author_Institution :
Grad. Sch. of Med., Dentistry & Pharm. Sci., Dept. of Biomater., Okayama Univ., Okayama, Japan
Abstract :
In this study we performed a microRNA (miRNA) array to characterize a stem cell population from human dental pulp-derived mesenchymal stromal cells (hDPSCs). miRNA-720 was found to regulate the stem cell phenotype of hDPSCs by targeting the pluripotency factor NANOG.
Keywords :
RNA; cellular biophysics; dentistry; molecular biophysics; proteins; human dental pulp-derived mesenchymal stromal cell differentiation; miRNA-720; microRNA array; pluripotency factor NANOG; stem cell phenotype; Arrays; Dentistry; Educational institutions; Sociology; Statistics; Stem cells; Vectors;
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2014 International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4799-6678-3
DOI :
10.1109/MHS.2014.7006080
