DocumentCode :
1794875
Title :
Microelectronic circuits analogous to hydrogen bonding networks in Michaelis complex of beta-lactamase protein
Author :
Gieva, E. ; Rusev, Rostislav ; Angelov, George ; Radonov, R. ; Hristov, Marin
Author_Institution :
Dept. of Microelectron., Tech. Univ. of Sofia, Sofia, Bulgaria
fYear :
2014
fDate :
7-11 May 2014
Firstpage :
278
Lastpage :
283
Abstract :
A microelectronic circuit of block-elements functionally analogous to two hydrogen bonding networks is investigated in the present paper. The hydrogen bonding networks are extracted from Michaelis complex of β-lactamase protein. They are described by electrical circuits. The hydrogen bonds of the networks are presented by three- or four-terminal block-elements in the juxtaposed electrical circuits. The block-elements are coded in Matlab with polynomials and static and dynamic analyses are performed. The circuits´ behavior appeared to be similar to current source or amplifier, and signal modulator.
Keywords :
hydrogen bonds; integrated circuit modelling; proteins; β-lactamase protein; Matlab; Michaelis complex; amplifier; beta-lactamase protein; circuit behavior; current source; electrical circuits; four-terminal block-elements; hydrogen bonding networks; microelectronic circuits; polynomials; signal modulator; three-terminal block-elements; Bonding; Equations; Hydrogen; Mathematical model; Microelectronics; Proteins; Springs;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Electronics Technology (ISSE), Proceedings of the 2014 37th International Spring Seminar on
Conference_Location :
Dresden
Type :
conf
DOI :
10.1109/ISSE.2014.6887608
Filename :
6887608
Link To Document :
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