Title :
Transcutaneous measurement of bio-substances by suction effusion fluid from skin
Author :
Kayashima, Shinsuke ; Arai, Tsunenori ; Kikuchi, Makoto ; Nagata, Naokazu ; Takatani, Osamu ; Miyamoto, Shageyuki ; Shinohara, Shio ; Ito, Narushi ; Kimura, Jun ; Kuriyama, Toshihide
Author_Institution :
Nat. Defense Med. Coll., Saitama, Japan
Abstract :
Successful transcutaneous blood glucose monitoring on human subjects has been achieved. Effusion fluid is collected from the skin using a recently developed suction apparatus, and glucose concentration in the fluid is measured. During a 75-g oral glucose tolerance test on normal subjects, frequent transcutaneous monitoring of blood glucose change was achieved with an improved ion-sensitive field effect transistor glucose sensor which can measure glucose concentration in only 5-μl samples
Keywords :
biomedical measurement; skin; bio-substances; ion-sensitive field effect transistor glucose sensor; normal subjects; oral glucose tolerance test; skin; suction effusion fluid; transcutaneous measurement; Biomedical monitoring; Blood; FETs; Humans; National electric code; Patient monitoring; Skin; Sugar; Testing; Volume measurement;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96102
