Title :
Focused ultrasonic transducer for localized sonodynamic therapy
Author :
Yasui, A. ; Haga, Y. ; Chen, J.J. ; Esashi, M. ; Wada, H.
Author_Institution :
Graduate Sch. of Eng., Tohoku Univ., Sendai, Japan
Abstract :
The aim of this study is to develop the focused ultrasonic transducers using a concave-shaped PZT for localized sonodynamic therapy in the human body. The concave-shaped PZT was fabricated from a bulk PZT using a high-speed micro-milling machine, and then repolarized for the optimized polarization direction. The measurement result of the acoustic field using a PVDF hydrophone indicated that the ultrasound emitted from the focused ultrasonic transducer was successfully focused in three-dimensions. At the focal point, the measured peak intensity would be sufficient for sonodynamic therapy.
Keywords :
biological effects of acoustic radiation; biomedical ultrasonics; piezoelectric transducers; radiation therapy; ultrasonic focusing; ultrasonic transducers; PVDF hydrophone; acoustic field; bulk piezoelectric transducer; concave shape; focused ultrasonic transducer; focused ultrasound; localized sonodynamic therapy; micromilling machine; polarization direction; Acoustic measurements; Biomedical engineering; Biomedical measurements; Focusing; Humans; Medical treatment; Probes; Ultrasonic imaging; Ultrasonic transducers; Ultrasonic variables measurement;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on
Print_ISBN :
0-7803-8994-8
DOI :
10.1109/SENSOR.2005.1497408
