Characterization of single red blood cell using twin microcantilever type sensor array

We have introduced a new biosensor device for red blood cell measurement by singular cell level with parallel analysis and high throughput. This paper deals with the practical measurement of red blood cells as well as the details on its fabrication, including device packaging. Based on a simple measurement of the electrical impedance of a living single red blood cell and its suspension, an important set of data, which can be used to describe living matter, could be obtained. It was confirmed that the electrical impedance between normal and abnormal red blood cells was significantly different in magnitude and phase shift.