Title :
Light-addressable potentiometric penicillin image sensor using the self-assembled monolayer immobilizing method
Author :
Jang, Su-Won ; Lee, Sun-Young ; Lee, Kwang-Man ; Kwon, Dae-Hyuk ; Kang, Shin-Won
Author_Institution :
Dept. of Electron. Eng., Kyungpook Nat. Univ., Daegu, South Korea
Abstract :
In this study, the LAPSs (light addressable potentiometric sensors) which have devices of Si3N4/SiO2/Si, Ta2O5/SiO2/Si structure were fabricated. Also, it was investigated the response characteristics to penicillin concentration and detected the 2D images of 128 × 128 pixels. The penicillinase was immobilized on the devices to hydrolyze the penicillin using self-assembled monolayer (SAM) method. The measuring system was simplified by using Lab VIEW software. The result of the enzyme reaction, the sensitivity of the sensor which has Si3N4 surfaces was 60 mV/decade and Ta2O5 surfaces was 74 mV/decade in the range of 0.1 mM ∼ 10 mM of the penicillin concentration. Image detecting time by an enzyme reaction between penicillin and penicillinase took about 10 minutes at 128 × 128 pixels in 1 × 1 cm sensing area.
Keywords :
biomedical measurement; biosensors; image sensors; monolayers; potentiometers; self-assembly; silicon compounds; tantalum compounds; 1 cm; 10 min; 128 pixels; 16384 pixels; 2D images; LAPS; Lab VIEW software; Si3N4-SiO2-Si; Ta2O5-SiO2-Si; enzyme reaction; image sensor; immobilizing method; light addressable potentiometric sensors; penicillin concentration; response characteristics; self-assembled monolayer; sensor sensitivity; Biochemistry; Biomembranes; Biosensors; Chemical and biological sensors; Image sensors; Insulation; Pixel; Sensor phenomena and characterization; Sensor systems; Software measurement;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on
Print_ISBN :
0-7803-8994-8
DOI :
10.1109/SENSOR.2005.1497433
